Serum levels of FGF21 are reduced and negatively correlated with adiponectin in children with Prader-Willi syndrome
نویسندگان
چکیده
Background/Aims FGF21 (fibroblast growth factor 21) is a novel metabolic regulator that has beneficial effects on glucose homeostasis and insulin sensitivity. In human obesity, serum FGF21 level was increased. The aims of this study were comparing fasting serum levels of FGF21 in Prader-Willi syndrome (PWS) and obese control children and finding correlations these levels with insulin sensitivity and obesity-related parameters.
منابع مشابه
Dental Management of Patients with Prader Willi Syndrome
Prader–Willi syndrome (PWS) is a genetic disorder which occurs with a frequency of about one in 10,000–30,000 live newborns. Both males and females, and all races are equally affected. PWS is a complex disorder with multiple disabilities, and the main defect is found in the hypothalamus. Child with PWS at the age between 2 and 3 years becomes constantly hungry and if the diet is not controlled,...
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ورودعنوان ژورنال:
دوره 2013 شماره
صفحات -
تاریخ انتشار 2013